The global active pharmaceutical ingredients market size is estimated to be USD 199.8 billion in 2020 and is expected to witness a CAGR of 5.957% during the forecast period. Growth in the adoption of AI-based tools for the discovery of new drugs is a key driver for the growth of the global active pharmaceutical ingredients market. Additionally, technological developments in the global API manufacturing and growing investment in R&D activities for new product development are some of the other drivers expected to propel the market growth. However, high costs of manufacturing APIs and increase in penetration of imitation drugs in the global market are expected to restrain the global market growth.
Global Active Pharmaceutical Ingredients Market Size (USD Million), 2021-2029
Source: Erevna Healthcare
By Type of Synthesis
Based on type of synthesis, the market is segmented into synthetic and biotech. In 2021, the synthetic API segment accounted for a substantial revenue share and is expected to grow with a lucrative CAGR during the forecast period. This can be attributed to the increase in accessibility of raw materials along with relaxed protocols for the production of these molecules worldwide. Biotech API segment is projected to grow at a profitable CAGR during the forecast period. This is attributed to the various advantages offered by this segment such as increase in demand for biopharmaceuticals coupled with the higher effectiveness of these molecules.
By Type of Manufacturers
Based on type of manufacturers, the market is segmented into merchant APIs and captive APIs. In 2021, the captive APIs segment accounted for the substantial revenue share with lucrative CAGR during the forecast period. This is attributed to rising accessibility to raw materials and widespread investments by major manufacturers for developing high-end industrialized facilities worldwide. Merchant APIs segment is projected to grow at a profitable CAGR during the forecast period. This is attributed to the fact that subcontracting of manufacturing to emerging countries is becoming very cost-effective, which allows these manufacturers to gain high profits.
By Type
Based on type, the market is categorized into innovative APIs and generic APIs. In 2021, the innovative APIs segment accounted for a substantial revenue share with lucrative CAGR during the forecast period. This is due to increase in R&D initiatives for new drug growth and favorable government guidelines worldwide. The generic APIs segment is anticipated to grow at a profitable CAGR during the forecast period due to the growing unmet clinical needs coupled with the approval of OTC drugs.
By Application
Based on application, the market is categorized into endocrinology, cardiovascular diseases, orthopedic, oncology, CNS and neurology, pulmonology, ophthalmology, gastroenterology, nephrology, and others. In 2021, the cardiovascular diseases segment accounted for the substantial revenue share and is estimated to grow with a lucrative CAGR during the forecast period. This is due to the rise in cases of target diseases worldwide. The oncology segment is anticipated to grow at a profitable CAGR during the forecast period due to changing lifestyle along with the rise in prevalence of cancer.
Regional Insights
In 2021, North America held the highest revenue share in the global market and is expected to maintain its dominance during the forecast period. This can be attributed to the increase in study and analysis of cancer coupled with lifestyle-induced diseases, growth in initiatives from the government, and accessibility of technologically advanced products in the region. Asia Pacific market is expected to grow at the fastest CAGR over the forecast period owing to the evolving market for biosimilars, growing government and corporate investment in healthcare sector, increase in travel tourism in developing economies, and market growth opportunities in developing countries, are the major factors in this region.
Competitor Insights
Some of the key players in the active pharmaceutical ingredients market are Pfizer, Inc. (U.S.); Novartis International AG (Switzerland); Sanofi (France); Boehringer Ingelheim (Germany); Bristol-Myers Squibb (U.S.); Teva Pharmaceutical Industries Ltd. (Israel); Eli Lilly and Company (U.S.); GlaxoSmithKline plc (U.K.); Merck & Co., Inc. (U.S.); AbbVie Inc. (U.S.); F. Hoffmann-La Roche Ltd. (Switzerland); AstraZeneca (U.K.); and Cipla, Inc. (India). The leading players operating in the active pharmaceutical ingredients industry are adopting various strategies including R&D investments, adaption of advanced techniques, new technology launches, mergers & acquisitions, and regional expansions to capture a maximum revenue share.
This exhaustive research report focuses on market size and forecast at global, segmental, regional and country level along with key market trends and dynamics from 2021 to 2029. The active pharmaceutical ingredients market report is categorized into the following segments and subsegments:
Active Pharmaceutical Ingredients Market, By Type of Synthesis (Revenue, USD Billion, 2021 – 2029)
- Synthetic
- Biotech
- Monoclonal Antibodies
- Recombinant Proteins
- Vaccines
Active Pharmaceutical Ingredients Market, By Type of Manufacturer (Revenue, USD Billion, 2021 – 2029)
- Merchant APIs
- Captive APIs
Active Pharmaceutical Ingredients Market, By Type (Revenue, USD Billion, 2021 – 2029)
- Innovative APIs
- Generic APIs
Active Pharmaceutical Ingredients Market, By Application (Revenue, USD Billion, 2021 – 2029)
- Endocrinology
- Cardiovascular Diseases
- Orthopedic
- Oncology
- CNS and Neurology
- Pulmonology
- Ophthalmology
- Gastroenterology
- Nephrology
- Others
Active Pharmaceutical Ingredients Market, By Region (Revenue, USD Billion, 2021 – 2029)
- North America
- U.S.
- Canada
- Europe
- Germany
- France
- UK
- Spain
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Australia
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of LATAM
- Middle East & Africa
- South Africa
- Saudi Arabia
- Rest of MEA
Scope of Active Pharmaceutical Ingredients Market Report:
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Table of Contents: Active Pharmaceutical Ingredients Market 2021-2029
- Research Methodology
- Study Objectives
- Study Scope
- Research Assumptions
- Research Framework
- Research Models
- Bottom-up Approach
- Top-down Approach
- Data Triangulation
- Data Procurement
- Internal Database
- Secondary Research
- Purchased Database
- Primary Research
- Data Analysis
- Data Validation
- Market Size Estimation
- Market Forecast Model
- Quality Assessment
- Research Models
- Introduction: Active Pharmaceutical Ingredients
- Executive Summary
- Global Market Scenario
- Segment Market Scenario
- Geographic Market Scenario
- COVID-19 Impact
- Competitive Landscape
- Market Dynamics
- Market Drivers
- Driver 1
- Driver 2
- Driver 3
- Driver 4
- Driver 5
- Market Restraint
- Restraint 1
- Restraint 2
- Restraint 3
- Restraint 4
- Market Opportunities
- Opportunity 1
- Opportunity 2
- Opportunity 3
- Opportunity 4
- Market Trends
- Trend 1
- Trend 2
- Trend 3
- Trend 4
- Market Challenges
- Challenge 1
- Challenge 2
- Challenge 3
- Challenge 4
- Market Drivers
- Market Environment Analysis
- Porter’s 5 Forces Analysis
- PESTEL Analysis
- Value Chain Analysis
- SWOT Analysis
- Benchmark
- COVID-19 Impact Analysis: Active Pharmaceutical Ingredients Market
- COVID-19: Overview
- COVID-19 Impact on the Global Market
- COVID-19 Impact on the Regional Markets
- Market Analysis by Type
- Generic APIs
- Generic APIs Market Forecast, 2021-2029 (USD Million)
- Innovative APIs
- Innovative APIs Market Forecast, 2021-2029 (USD Million)
- Generic APIs
- Market Analysis by Type of manufacturer
- Captive APIs
- Captive APIs Market Forecast, 2021-2029 (USD Million)
- Merchant APIs
- Merchant APIs Market Forecast, 2021-2029 (USD Million)
- Captive APIs
- Market Analysis by Type of synthesis
- Synthetic
- Synthetic Market Forecast, 2021-2029 (USD Million)
- Biotech
- Biotech Market Forecast, 2021-2029 (USD Million)
- Synthetic
- Market Analysis by Application
- Oncology
- Oncology Market Forecast, 2021-2029 (USD Million)
- Endocrinology
- Endocrinology Market Forecast, 2021-2029 (USD Million)
- Orthopedic
- Orthopedic Market Forecast, 2021-2029 (USD Million)
- CNS & Neurology
- CNS & Neurology Market Forecast, 2021-2029 (USD Million)
- Nephrology
- Nephrology Market Forecast, 2021-2029 (USD Million)
- Gastroenterology
- Gastroenterology Market Forecast, 2021-2029 (USD Million)
- Pulmonology
- Pulmonology Market Forecast, 2021-2029 (USD Million)
- Cardiovascular Diseases
- Cardiovascular Diseases Market Forecast, 2021-2029 (USD Million)
- Ophthalmology
- Ophthalmology Market Forecast, 2021-2029 (USD Million)
- Others
- Others Market Forecast, 2021-2029 (USD Million)
- Oncology
- Regional Market Analysis
- Regional Market Trends
- Regional Market: Comparative Analysis
- North America Active Pharmaceutical Ingredients Market
- North America Active Pharmaceutical Ingredients Market
- North America Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- S. Active Pharmaceutical Ingredients Market
- S. Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Canada Active Pharmaceutical Ingredients Market
- Canada Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Canada Market Size and Forecast, 2021-2029 (USD Million)
- S. Market Size and Forecast, 2021-2029 (USD Million)
- North America Market Size and Forecast, 2021-2029 (USD Million)
- North America Active Pharmaceutical Ingredients Market
- Europe Active Pharmaceutical Ingredients Market
- Europe Active Pharmaceutical Ingredients Market
- Europe Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Germany Active Pharmaceutical Ingredients Market
- Germany Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- UK Active Pharmaceutical Ingredients Market
- UK Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- France Active Pharmaceutical Ingredients Market
- France Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Spain Active Pharmaceutical Ingredients Market
- Spain Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Italy Active Pharmaceutical Ingredients Market
- Italy Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Europe Active Pharmaceutical Ingredients Market
- Rest of Europe Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Europe Market Size and Forecast, 2021-2029 (USD Million)
- Italy Market Size and Forecast, 2021-2029 (USD Million)
- Spain Market Size and Forecast, 2021-2029 (USD Million)
- France Market Size and Forecast, 2021-2029 (USD Million)
- UK Market Size and Forecast, 2021-2029 (USD Million)
- Germany Market Size and Forecast, 2021-2029 (USD Million)
- Europe Market Size and Forecast, 2021-2029 (USD Million)
- Europe Active Pharmaceutical Ingredients Market
- Asia Pacific Active Pharmaceutical Ingredients Market
- Asia Pacific Active Pharmaceutical Ingredients Market
- Asia Pacific Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Japan Active Pharmaceutical Ingredients Market
- Japan Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- China Active Pharmaceutical Ingredients Market
- China Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- India Active Pharmaceutical Ingredients Market
- India Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- South Korea Active Pharmaceutical Ingredients Market
- South Korea Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Australia Active Pharmaceutical Ingredients Market
- Australia Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Asia Pacific Active Pharmaceutical Ingredients Market
- Rest of Asia Pacific Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Asia Pacific Market Size and Forecast, 2021-2029 (USD Million)
- Australia Market Size and Forecast, 2021-2029 (USD Million)
- South Korea Market Size and Forecast, 2021-2029 (USD Million)
- India Market Size and Forecast, 2021-2029 (USD Million)
- China Market Size and Forecast, 2021-2029 (USD Million)
- Japan Market Size and Forecast, 2021-2029 (USD Million)
- Asia Pacific Market Size and Forecast, 2021-2029 (USD Million)
- Asia Pacific Active Pharmaceutical Ingredients Market
- Latin America Active Pharmaceutical Ingredients Market
- Latin America Active Pharmaceutical Ingredients Market
- Latin America Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Brazil Active Pharmaceutical Ingredients Market
- Brazil Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Mexico Active Pharmaceutical Ingredients Market
- Mexico Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type , 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Argentina Active Pharmaceutical Ingredients Market
- Argentina Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Latin America Active Pharmaceutical Ingredients Market
- Rest of Latin America Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of Latin America Market Size and Forecast, 2021-2029 (USD Million)
- Argentina Market Size and Forecast, 2021-2029 (USD Million)
- Mexico Market Size and Forecast, 2021-2029 (USD Million)
- Brazil Market Size and Forecast, 2021-2029 (USD Million)
- Latin America Market Size and Forecast, 2021-2029 (USD Million)
- Latin America Active Pharmaceutical Ingredients Market
- MEA Active Pharmaceutical Ingredients Market
- MEA Active Pharmaceutical Ingredients Market
- MEA Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- GCC Active Pharmaceutical Ingredients Market
- GCC Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- South Africa Active Pharmaceutical Ingredients Market
- South Africa Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of MEA Active Pharmaceutical Ingredients Market
- Rest of MEA Market Size and Forecast, 2021-2029 (USD Million)
- Market Size and Forecast by Type, 2021-2029 (USD Million)
- Market Size and Forecast by Type of manufacturer , 2021-2029 (USD Million)
- Market Size and Forecast by Type of synthesis, 2021-2029 (USD Million)
- Market Size and Forecast by Application, 2021-2029 (USD Million)
- Rest of MEA Market Size and Forecast, 2021-2029 (USD Million)
- South Africa Market Size and Forecast, 2021-2029 (USD Million)
- GCC Market Size and Forecast, 2021-2029 (USD Million)
- MEA Market Size and Forecast, 2021-2029 (USD Million)
- MEA Active Pharmaceutical Ingredients Market
- Competitor Analysis
- Market Share Analysis, 2020 & 2031
- Competitive Mapping
- Key Players Market Place Analysis
- Major Recent Developments
- Company Profiles
- Pfizer, Inc. (US)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Novartis International AG (Switzerland)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Sanofi (France)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Teva Pharmaceutical Industries Ltd. (Israel)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Eli Lilly and Company (US)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- GlaxoSmithKline plc (UK)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- AbbVie Inc. (US)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Cipla, Inc. (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Sun Pharmaceutical Industries Ltd. (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Merck & Co., Inc. (US)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Mylan N.V. (US)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Reddy’s Laboratories Ltd. (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Sun Pharmaceutical Industries Ltd. (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- API Pharma Tech (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- BDR Pharmaceuticals Internationals Pvt. Ltd. (India)
- Company Snapshot
- Company Overview
- Financials
- Product Benchmarking
- Recent Developments
- Others Prominent Players
- Pfizer, Inc. (US)
Conclusion & Recommendations