The global downstream processing market size is estimated to be USD 24.78 billion in 2021 and is expected to witness a CAGR of 16.75% during the forecast period. Rising demand for recombinant products including biologics, vaccines, and biosimilars is a key driver for the growth of the global downstream processing market. Additionally, increase in penetration of large molecules & biologics and investments in R&D are some of the other drivers propelling the market growth. However, the high cost of drug development & manufacturing process and lack of skilled professional are expected to restrain the global market growth.

By Product

Based on product, the market is segmented into centrifuges, chromatography systems, evaporators, filters, dryers, and others. In 2021, the chromatography segment accounted for a significant revenue share and is anticipated to grow with a lucrative CAGR during the forecast period. This is attributed to the cost-effectiveness and convenient implementation of technique. Filters segment is projected to grow at a profitable CAGR during the forecast period. This is attributed to its benefit of eliminating substitute separation and purification techniques as well as providing viral safety during downstream processing.

By Technique

Based on technique, the market is categorized into concentration, cell disruption, solid-liquid separation, formulation, and purification by chromatography. In 2021, the purification by chromatography method accounted for a significant revenue share as chromatography is the key step in downstream purification worldwide. The solid-liquid separation segment is anticipated to grow at the fastest CAGR during the forecast period, due to the increasing technological advancements in filtration technique.

By Application

Based on application, the market is categorized into hormone production, antibiotic production, antibodies production, vaccine production, and enzyme production. The antibiotic production segment accounted for a highest revenue share in 2021 and is projected to maintain its dominance over the forecast period. Rising prevalence of infectious diseases, especially during the COVID-19 pandemic, is a key factor that is expected to drive the segment growth. The antibodies production segment is anticipated to grow at the fastest CAGR during the forecast period, due to introduction of strong platforms for the production of monoclonal antibodies (MABs) via mammalian cultures.

Regional Insights

In 2021, North America accounted for the highest revenue share in the global market and is expected to maintain its dominance during the forecast period. This is attributed to the government aid for bioprocessing technique awareness, presence of leading biopharmaceutical companies, and progressive healthcare infrastructure in this region. Asia Pacific market is projected to exhibit the fastest CAGR over the forecast period owing to the growing focus of biopharmaceutical companies in this region. Countries such as India, Japan, and China are strengthening their medical infrastructure capabilities and making heavy investments in the field of biotechnology.

Competitor Insights

Some of the key players in the downstream processing market are Asahi Kasei Corporation (Japan); Corning Incorporated (U.S.); Eppendorf (Germany); Lonza Group AG (Switzerland); C. H. Boehringer Sohn AG & Co. KG (Germany); Repligen (U.S.); 3M Company (U.S.); Danaher Corporation (U.S.); Merck KGaA (Germany), Sartorius AG (Germany), Thermo Fisher Scientific (U.S.) and General Electric Company (U.S.). The leading players operating in the downstream processing industry are adopting various strategies including R&D investments, collaborations, adoption of advanced techniques, and mergers & acquisitions to capture a maximum revenue share.

This exhaustive research report focuses on market size and forecast at global, segmental, regional and country level along with key market trends and dynamics from 2021 to 2029. The downstream processing market report is categorized into the following segments and subsegments:

Downstream Processing Market, By Product (Revenue, USD Billion, 2021 – 2029)

• Centrifuges
• Chromatography Systems
• Evaporators
• Filters
• Dryers
• Others

Downstream Processing Market, By Technique (Revenue, USD Billion, 2021 – 2029)

• Concentration
  • Evaporation
  • Membrane filtration
• Cell Disruption
• Solid-liquid separation
  • Filtration
  • Centrifugation
• Formulation
• Purification by Chromatography

Downstream Processing Market, By Application (Revenue, USD Billion, 2021 – 2029)

• Hormone Production
• Antibiotic Production
• Antibodies Production
• Vaccine Production
• Enzyme Production

Downstream Processing Market, By Region (Revenue, USD Billion, 2021 – 2029)

• North America
  • US
  • Canada
• Europe
  • Germany
  • France
  • UK
  • Spain
  • Italy
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of APAC
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of LATAM
• Middle East & Africa
  • South Africa
  • Saudi Arabia
  • Rest of MEA

Scope of Downstream Processing Market Report:

Key Parameters	Details
Base Year	2021
Forecast Period	2022-2029
Study Coverage	Global and regional market size and revenue forecast Segment market size and revenue forecast at global, regional, and country level Competitive landscape (company share analysis, company profiles, recent development, competitive map analysis) Conclusion and recommendations
Qualitative Analysis	Market drivers Market restraints Market opportunities Recent market trends Market challenges Porter’s Five Forces analysis PEST analysis Value-chain analysis COVID-19 impact analysis
Regional Market Scope	North America (U.S. and Canada) Europe (Germany, France, UK, Spain, Italy, Russia, Rest of Europe) Asia Pacific (China, Japan, India, Australia, South Korea, Rest of APAC) Latin America (Brazil, Mexico, Argentina, Rest of LATAM) MEA (South Africa, GCC, Rest of MEA)
Company Profiles	Exhaustive profiles of top 15 players 50+ other major players listing
15% Free Customization Available	You can customize the study scope to meet your exact requirement. Click here for more details